The Effect of Short-Term Coenzyme Q10 Supplementation on Malondialdehyde and Serum Catalase ‎Enzyme Activity Following Moderate and Severe Acute Resistance Training Inactive Female Students

Background and Objectives: It has been reported that antioxidant supplementation may reduce the oxidative stress caused by exercise activities. But according to the type of activity, dose and type of supplement, the results in this area are contradictory. The aim of this study was to investigate the effect of short-term coenzyme Q10 supplementation on malondialdehyde (MDA) and serum catalase enzyme activity following moderate and severe acute resistance training in inactive female students. Methods: Twenthy seven non-active female students were selected to participate in the study. They were randomly divided into homogeneous and equal groups (two groups of resistance and one control group). The control group did not intervene; however, experimental groups of the study were included moderate acute resistance (70% 1RM) and severe acute resistance training (85% 1RM) which consumed Q10 as 30 mg/d. The MDA and catalase indices were measured by ELISA method and the results were analyzed by repeated ANOVA, Bonferroni and independent t-tests at p <0.05. Results: Moderate and severe acute resistance trainings did not change the MDA and catalytic activity, but moderate and severe acute and moderate acute resistance training with reduces MDA (p = 0.01 and p = 0.06) and catalase (p = 0.004 and p = 0.007), but between the effects of two acute resistance trainings and the effect of two types of acute resistance trainings along with supplementation on these variables no significant difference was observed. Conclusion: Coenzyme Q10 supplementation reduces these two indices and prevents undesirable and proba ble free radical effects.